Surfactant for meconium aspiration syndrome in term and late preterm infants

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Meconium aspiration syndrome in neonates

Perhaps the most significant changes in airway management over the recent years have been in the management of an infant delivered through meconium- stained amniotic fluid( MSAF). MSAF occurs in approximately 10℅ to 20℅ of all deliveries and increases to over 30℅ in deliveries after 42 weeks gestation. Meconium aspiration syndrome ( MAS) occurs in about 2℅ to 5℅ of these cases with a high morta...

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Meconium aspiration syndrome.

In the years 1977-82, 43 infants with the meconium aspiration syndrome (MAS) were managed at the Department of Paediatrics of Turku University Central Hospital (TUCH), Finland. Among 5,353 deliveries in one year the incidence of meconium staining was 8.7%. By extrapolation, the incidence of meconium aspiration in all newborns is approximately 0.13%. The mean duration of the pregnancies was 39.2...

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Meconium aspiration syndrome.

We agree that the passage of meconium in utero is not always due to intrauterine asphyxia and it may be a purely physiological event due to increasing maturity of the fetus. However, a bacterial endotoxin has been recently implicated in "causing the preterm labor and passage of meconium in utero(3). It is to be emphasized that only those neonates who have respiratory\distress with radiological ...

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Surfactant therapy in late preterm infants: respiratory distress syndrome and beyond.

A significant ratio of late preterm infants receives surfactant therapy (ST) for respiratory distress syndrome (RDS) and for other neonatal lung diseases characterized by surfactant inactivation or dysfunction. We aimed to investigate the clinical and therapeutic characteristics and outcomes of late preterm infants who received ST in the last 10 years in our neonatal intensive care unit. During...

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Moderately preterm, late preterm and early term infants: research needs.

In spite of increased appreciation that all preterm infants and early term infants are at higher risk for mortality and morbidities compared with their term counterparts, there are many knowledge gaps affecting optimal clinical care for this vulnerable population. This article presents a research agenda focusing on the systems biology, epidemiology, and clinical and translational sciences on th...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2014

ISSN: 1465-1858

DOI: 10.1002/14651858.cd002054.pub3